The Food and Drug Administration is warning consumers to avoid taking the erectile dysfunction drug Cialis and its generic equivalent, Levitra, over the counter.
FDA said Wednesday it is requiring insurers to provide information about potential drug interactions that could lead to increased use of the drugs. The agency is also reviewing the safety of some other erectile dysfunction medications.
The warning comes just two months after a federal appeals court in Texas ruled the drugs should not be sold in a generic form, because of possible health risks.
The FDA is still investigating the issue and has not decided whether to require the makers of Cialis and Levitra to disclose more information about potential interactions to consumers.
The agency said consumers who use these drugs regularly may be able to stop taking the drugs at any time.
The Food and Drug Administration has not said what consumers with diabetes, high blood pressure, or kidney disease should be able to safely use.
The FDA said it is investigating whether consumers with a history of heart disease, high blood pressure, or high cholesterol should be able to safely take the drugs.
The drugmakers that sell Cialis and Levitra have not commented on the FDA's position on the issue. It was not immediately available Tuesday evening.
The company said the agency is "reviewing the safety profile of all available products."
Copyright 2023 The Associated Press. All rights reserved. This materialroximately listed reporters do not need to be endorsed.
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https://twitter.com/LionyCialis_or_Viagra_generic.com/http://www.levitra-online.com/wp-content/uploads/2017/03/generic-generic-tadalafil.htmlhttps://www.levitra-online.com/wp-content/uploads/2013/06/generic-generic-tadalafil.htmlhttp://www.fda.gov/Safety/Drugs/DrugSafetyness/DrugSafetyness-Oral-Suspensions/Safety-Oral-Suspensions-Overnight-Treating-Headache/https://www.fda.gov/Safety/DrugSafety/DrugSafetyness/DrugSafetyness-Oral-Suspensions/Safety-Oral-Suspensions-Overnight-Treating-Headache/https://www.twitter.com/LionyCialis_or_Viagra_generic.com/https://www.youtube.com/watch?v=d-zSx2qwv4qIoshttps://www.levitra-online.com/wp-content/uploads/2013/11/generic-tadalafil.htmlhttps://www.levitra-online.com/wp-content/uploads/2017/03/generic-tadalafil.htmlhttps://www.twitter.com/LionyCialis_or_Viagra_generic.com/watch?v=d-zSx2qw4IosCialis is one of the most well-known drugs on the market, and in the U. S. is currently approved for use as an erectile dysfunction treatment. It is available for purchase by prescription only, and the drug is available as a generic.
https://www.youtube.com/watch?v=d-zSx2qw4IosWatch?v=d-zSx2qw4Ioshttps://www.IMPORTANT NOTICE: Please be aware, prior to sale, you are advised to have a short phone call consultation with our Pharmacist. Automatic purchase consents the Pharmacist to give you a quick call.
Viagra Connect is available without a Prescription but requires a brief consultation with the Pharmacist. It is available in a 4 pack or an 8 pack. Viagra Connect contains Sildenafil 50mg which works by relaxing the penis blood vessels, allowing blood to flow when you get aroused causing erections and potency. Viagra Connect will only help men become erect if you are aroused. Only for adult use, men 18 years plus.
How to be taken:
VIAGRA CONNECT is not to be taken if:
Please read instructions carefully provided.
Viagra Connect is a fast acting drug for erectile dysfunction which can last up to 4 hours and takes effect within 30 minutes after administration.
Sildenafil Citrate 50 mg Tablets: This tablet is specifically formulated to treat the symptoms of erectile disfunction and is highly effective in treating it, the most common sexual disorder affecting men over the age of 40 years. Provides a solution to erectile dysfunction in men who suffer from impotence due to conditions such as heart disease or diabetes, or who have problems with their physical or mental health.
Viagra Connect ensures fast and effective results that last as long as 36 hours and come without side effects. It works by relaxing the blood vessels in the penis, allowing blood to flow into the phallus when you get sexually excited and causing the desired stiffness.
Add this medicine to your diet within 6 weeks of taking Viagra Connect. If you experience side effects such as decreased erections, headache, back pain, muscle pain or nausea after taking Viagra Connect, do not take them.Please read instructions carefully provided as part of your overall sexual life. The dose should be taken one hour before you plan to have sex. The Pharmacist will discuss with you the risks and benefits of taking Viagra Connect with the added layer of readability (ilt down the calf of your lower leg to the side of your stomach) of both meals and of your body. The pharmacist will provide you with a safe and suitable solution for the treatment of erectile dysfunction.
The study was designed to help determine whether the use of sildenafil citrate, the active ingredient in the FDA-approved drug Viagra, could have an effect on sexual performance. Viagra and its derivatives, which are chemically similar to sildenafil, are widely used for erectile dysfunction. Sildenafil citrate is a PDE-5 inhibitor, a drug designed to relax the blood vessels in the penis. Sildenafil citrate is also known as sildenafil and is the active ingredient in the FDA-approved drug for erectile dysfunction. However, the study was designed to determine whether the use of sildenafil citrate could have an effect on sexual performance, and the results should be interpreted cautiously.
In this study, patients with erectile dysfunction were enrolled and randomly assigned to receive sildenafil citrate (10 mg) or placebo for three consecutive months. The patients were followed up for an average of 12 months. The study was performed in accordance with the Declaration of Helsinki and in accordance with the Good Clinical Practice guidelines. The Ethics Committee of the Faculty of Pharmacy, University of Medicine and Medical Center, Wuhan, Wuhan, China, approved the study and the study was registered on the Clinical Trial Registry in Chinese Clinical Trial Register (CNPRCT097311180008, NCT0450257700).
Sildenafil citrate was administered orally in a dose range of 20 mg to 80 mg three times daily. Patients who did not achieve an erection during treatment with sildenafil citrate were not prescribed sildenafil citrate. The drug was dissolved in a normal saline solution, and the solution was then diluted with sterile normal saline. Sildenafil citrate was dissolved in 5 mL of saline solution to obtain a concentration of 50 mg/mL. The sildenafil citrate concentration in the diluent was then measured and analyzed using a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method. The analytes that were detected were analyzed using a validated LC-MS/MS method (C18; C18-C18-C18-C18).
A total of 120 patients were enrolled in the study, and the mean age of the participants was 53.7 years (range, 23–85 years). The mean age of the participants was significantly higher in the group treated with sildenafil citrate (p<0.001) than in the group treated with placebo (p<0.001). The mean duration of erectile dysfunction was 3.1 years (range, 2–5 years). There were no significant differences in the mean duration of sexual arousal, duration of sexual abstinence, or duration of erection between the two groups. The patients were treated with sildenafil citrate for six months.
The results showed that there was a statistically significant increase in the mean number of spontaneous erections (p<0.001), duration of sexual arousal (p<0.001), and duration of erection (p<0.001) in patients who received sildenafil citrate. The mean number of spontaneous sexual events (p<0.001) in the patients who received sildenafil citrate was significantly higher than in the patients who received placebo (p<0.001). However, there were no significant differences in the number of spontaneous sexual events between the two groups.
The results of the analysis of the statistical analysis showed that sildenafil citrate was associated with significantly more erections than placebo (p<0.001), duration of sexual arousal (p<0.001), and duration of erection (p<0.001) in all subjects.
The patients who received sildenafil citrate showed a significantly lower mean number of spontaneous sexual events (p<0.001) and duration of sexual abstinence (p<0.001). The mean number of spontaneous sexual events in the patients who received sildenafil citrate was significantly lower than in the patients who received placebo (p<0.001). The patients who received sildenafil citrate were more likely to have a reduced frequency of sexual intercourse (p<0.001). The patients who received sildenafil citrate had significantly more than placebo (p<0.001).
A total of 120 patients were enrolled and randomly assigned to receive sildenafil citrate (10 mg) or placebo for three consecutive months.
1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
Although the above interactions are generally considered safe, they do not necessarily mean you are free to use them. Always consult with a doctor or pharmacist before taking or using any medication.
Please note: interactions with other drugs have a possibility of side effects. We recommend consulting your doctor before starting any new medication.
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